New gene therapy aims to fix bone marrow in rare telomere disease

NCT ID NCT04211714

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 30 times

Summary

This early-phase study tests a new treatment called EXG34217 in 12 people aged 12 and older who have bone marrow failure due to telomere biology disorders. The main goal is to see if the treatment is safe and tolerable. Researchers will also check if it improves blood cell counts and telomere length.

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Contacts and locations

Locations

  • Cincinnati Children's Hospital

    Cincinnati, Ohio, 45229, United States

Conditions

Explore the condition pages connected to this study.