One-Shot gene therapy could end frequent eye injections for wet AMD

NCT ID NCT07178249

First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 27 times

Summary

This study tests a gene therapy called EXG202 for people with wet age-related macular degeneration (nAMD). The goal is to see if a single injection can safely deliver a protein that blocks harmful blood vessel growth, potentially reducing the need for repeated eye injections. The trial will enroll 60 adults aged 50 and older with active nAMD and will monitor safety and vision changes over one year.

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