New drug combo aims to slow rapid aging in kids

NCT ID NCT02579044

First seen Apr 11, 2026 · Last updated May 13, 2026 · Updated 4 times

Summary

This study tests adding everolimus to the standard drug lonafarnib for children with progeria, a rare condition that causes rapid aging. The goal is to find the safest dose and see if the combination improves weight gain and blood vessel health. About 80 participants will take part at Boston Children's Hospital.

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Contacts and locations

Locations

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.