New Botox-Like shot could loosen stiff arms in stroke survivors
NCT ID NCT07242300
First seen Jun 26, 2026 · Last updated Aug 06, 2026 · Updated 3 times
Summary
This Phase 3 trial tests a new botulinum toxin injection called Eveotox in 207 adults with upper limb spasticity (stiff muscles) after a stroke. The goal is to see if it reduces muscle tightness and improves daily tasks like dressing or hygiene compared to a placebo. Participants receive one injection and are followed for safety and effectiveness over several weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Recombinant botulinum toxin type A (Eveotox)
- What this could lead to
- If it works, this could provide a new treatment option to reduce muscle tightness and improve daily activities like dressing or hygiene for people with post-stroke spasticity.
- What could go wrong
- This is an early Phase 3 trial with only 207 participants, so results may not apply to everyone. The treatment is temporary and may cause side effects like muscle weakness or injection site reactions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Beijing Tsinghua Changgung Hospital
NOT_YET_RECRUITINGBeijing, Beijing Municipality, China
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Huai 'an Second People's Hospital
ACTIVE_NOT_RECRUITINGHuai'an, Jiangsu, China
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Huashan Hospital Fudan University
RECRUITINGShanghai, Shanghai Municipality, China
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Luoyang Central Hospital
RECRUITINGLuoyang, Henan, China
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Pingxiang People's Hospital
RECRUITINGPingxiang, Jiangxi, China
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Shengjing Hospital affiliated to China Medical University
RECRUITINGShenyang, Liaoning, China
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The Second Affiliated Hospital of Soochow University
RECRUITINGSuzhou, Jiangsu, China
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The Second Affiliated Hospital of Zhengzhou University
RECRUITINGZhengzhou, Henan, China
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The Second Hospital of Hebei Medical Hospital
RECRUITINGShijiazhuang, Hebei, China
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The Second Xiangya Hospital of Central South University
RECRUITINGChangsha, Hunan, China
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Yangzhi Affiliated Rehabilitation Hospital of Tongji University
RECRUITINGShanghai, Shanghai Municipality, China
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Yantai Mountain Hospital
RECRUITINGYantai, Shandong, China
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