New patch stops bleeding fast in Kids' surgeries
NCT ID NCT03255174
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a patch called EVARREST that helps stop mild to moderate bleeding during open surgery in children. The patch contains natural proteins that help blood clot. In 35 children, the patch stopped bleeding quickly, often within 4 minutes. The results suggest it is a safe and effective tool for surgeons.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- EVARREST Fibrin Sealant Patch (a patch with human fibrinogen and thrombin to stop bleeding)
- What this could lead to
- If successful, this could provide a safe and effective way to control bleeding during surgery in children, reducing the need for other methods.
- What could go wrong
- This is a small, completed Phase 3 trial with only 35 participants. Results may not apply to all children or all types of bleeding. There is always a risk of allergic reactions or the patch not working.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Birmingham Chrildren's Hospital
Birmingham, B4 6NH, United Kingdom
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Newcastle upon Tyne Hospitals NHS Foundation Trust
Newcastle upon Tyne, NE1 4LP, United Kingdom
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Southampton University Hospital
Southampton, SO16 6YD, United Kingdom
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University of Alabama Hospital
Birmingham, Alabama, 35222, United States
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icahn School of Medicine at Mt Sinai
New York, New York, 10029, United States