New heat treatment could replace surgery for rare pancreatic tumors
NCT ID NCT05735912
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares a less invasive procedure called endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) with standard surgery for treating pancreatic insulinoma, a rare tumor that causes low blood sugar. About 60 adults with small tumors (≤2 cm) will be randomly assigned to one of the two treatments. The goal is to see if EUS-RFA is safer and just as effective as surgery in relieving symptoms and preventing recurrence.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Radiofrequency ablation (a procedure using heat to destroy tumor cells)
- What this could lead to
- If successful, this could offer a safer, less invasive alternative to surgery for small pancreatic insulinomas, reducing hospital stays and recovery time.
- What could go wrong
- This is a relatively small trial (60 people) and the procedure may not be as effective as surgery in the long term, with possible tumor recurrence or incomplete symptom relief.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Hospital of Verona
Verona, 37138, Italy