Thin vs. thick needle: which is better for liver biopsy?
NCT ID NCT06643520
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at two different needle sizes used to take liver tissue samples during an endoscopy procedure. The goal was to see which needle gives better samples for diagnosing liver disease. 82 patients with unexplained high liver enzymes took part, and each had samples taken with both needles during the same procedure.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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82 people
The number who actually took part.
- Started
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Jul 2024
- Finished
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Apr 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All patients with unexplained elevation of liver enzymes and suspected hepatic paranchymal disease Exclusion Criteria: * Patients who had malignancy * Patients who have decompensated cirrhosis * Presence of ascites * Patients with coagulopathy (platelets \< 50.000 μ/ mL and INR \> 1.5) * The use of anticoagulant agents * Pregnancy * Unable to provide written informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Duzce University
Düzce, Düzce, 81620, Turkey (Türkiye)
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