Could a cool eye zap away chronic pain?
NCT ID NCT07059754
First seen Jan 10, 2026 · Last updated Jun 19, 2026 · Updated 26 times
Summary
This small study tests a device that cools the eye surface for 4 minutes in people with chronic ocular surface pain. Researchers will take images of the eye's nerves and collect tear samples to see what changes occur. Only 5 participants will be enrolled, and they will be followed for 12 weeks after a single treatment.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sunshine Eye Surgeons
RECRUITINGMelbourne, Victoria, 3021, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ETX-4143 topical ophthalmic cooling device
What this could lead to
If it works, this could point toward a non-drug way to ease chronic eye pain by cooling the eye surface.
What could go wrong
This is a very early feasibility study with only 5 people. It is not designed to prove the device works for pain relief, only to see if it changes eye structures and inflammation.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.