New hope for sickle cell brains: drug boosts blood flow in small trial

NCT ID NCT05725902

First seen Jan 07, 2026 · Last updated May 12, 2026 · Updated 14 times

Summary

This study tested a drug called etavopivat in 12 children and young adults (ages 12–21) with sickle cell disease. The goal was to see if it could improve blood flow and oxygen delivery to the brain and muscles. Participants took the drug for a period, and researchers measured changes in brain blood flow and oxygen use. The study was small and early-stage, so results help guide future research rather than proving a cure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SICKLE CELL DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Emory University Children's Healthcare of Atlanta

    Atlanta, Georgia, 30342, United States

Conditions

Explore the condition pages connected to this study.