Cell sheet trial for esophageal cancer patients ends early with just one volunteer

NCT ID NCT04689594

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a treatment using a sheet of the patient's own mouth cells to prevent the esophagus from narrowing after cancer removal surgery. Only one person took part before the study was stopped early. The goal was to see if the cell sheet could safely reduce scarring and keep the esophagus open.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Human (autologous) oral mucosal cell sheet

What this could lead to

If it works, this could offer a way to prevent esophageal narrowing after cancer surgery, reducing the need for repeated procedures.

What could go wrong

The trial was terminated early with only 1 participant, so results are very limited. It is unclear if the treatment is effective or safe in a larger group.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SUPERFICIAL ESOPHAGEAL CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

esophagus carcinoma in situ

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Okayama University Hospital

    Okayama, 700-8558, Japan