New combo therapy trial aims to boost survival for tough esophageal cancer

NCT ID NCT04848753

First seen Apr 10, 2026 · Last updated Apr 19, 2026 · Updated 1 time

Summary

This large, late-stage study is testing if adding an immunotherapy drug called toripalimab to standard chemotherapy, given both before and after surgery, works better than chemotherapy alone for people with a type of advanced esophageal cancer. The goal is to see if this combination helps keep the cancer from coming back longer and helps patients live longer. About 660 participants will be randomly assigned to receive either the real immunotherapy drug or a placebo alongside their chemotherapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for RESECTABLE LOCALLY ADVANCED THORACIC ESOPHAGEAL SQUAMOUS CELL CARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • 3201 Hospital

    Hangzhou, China

  • Affiliated Tumor Hospital of Xinjiang Medical University

    Ürümqi, Xinjiang, China

  • Anhui Provincial Cancer Hospital

    Hefei, China

  • Anhui provincial hospital

    Hefei, Anhui, 230001, China

  • Anyang Cancer Hospital

    Anyang, Henan, China

  • Beijing Cancer Hospital

    Beijing, China

  • China-Japan Union hosptial of Jilin university

    Changchun, Jilin, 130031, China

  • Fujian Cancer Hospital

    Fuzhou, China

  • Henan Cancer Hospital

    Zhengzhou, China

  • Henan provincial pepples hospital

    Zhengzhou, Henan, 450003, China

  • Heping Hospital Affiliated to changzhi Medical College

    Changzhi, China

  • Huai'an First People's Hospital

    Huai'an, China

  • Hubei Cancer Hospital

    Wuhan, China

  • Hunan provincial cancer hospital

    Changsha, Hunan, 410013, China

  • Hwa Mei Hospital,University of Chinese Academy of sciences

    Ningbo, Zhejiang, 315010, China

  • Jiangmen central Hospital

    Jiangmen, Guangdong, China

  • Jiangsu Cancer Hospital

    Nanjing, China

  • Liaoning cancer hospital& Institute

    Shenyang, China

  • Peking University Third Hospital

    Beijing, China

  • Renmin Hospital of Wuhan University

    Wuhan, China

  • Shantou University Cancer Hospital

    Shantou, China

  • Shanxi provincial cancer hosptial

    Taiyuan, Shanxi, 030013, China

  • Shengjing Hospital of China Medical University

    Shenyang, China

  • Shenzhen people's hosptial

    Shenzhen, Guangdong, 518040, China

  • Sichuan Cancer Hospital & Institute

    Chengdu, China

  • Taizhou hospital of zhejiang province

    Taizhou, Zhejiang, 317000, China

  • The Affiliated Hospital of Qingdao University

    Qingdao, China

  • The Affiliated Hospital of jining Medical University

    Jining, China

  • The Affiliated Hospital of xuzhou Medical University

    Xuzhou, China

  • The Firest Affiliated Hospital of bengbu Medical College

    Bengbu, Anhui, China

  • The First Affiliated Hospital of Xiamen University

    Xiamen, China

  • The First Affiliated Hospital of nanchang University

    Nanchang, China

  • The First Affiliated Hospital of xinxiang Medical University

    Xinxiang, Henan, China

  • The First Affiliated Hospital, Zhejiang University School of Medicine

    Hanzhou, China

  • The General Hospital of People's Liberation Army

    Beijing, China

  • The Second Hospital of anhui Medical University

    Hefei, Anhui, China

  • The first Hospital of china Medical University

    Shenyang, China

  • The first affilated hospital of zhengzhou university

    Zhengzhou, Henan, 450052, China

  • The first affiliated hospital of jinzhou medical university

    Jinzhou, Niaoning, 121001, China

  • The fourth hospital of hebei medical university

    Shijiazhuang, Hebei, 050019, China

  • Tianjin Medical University Cancer Institute and Hospital

    Tianjin, China

  • Union Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology

    Wuhan, China

  • Xinyang central Hospital

    Xinyang, China

  • Yantai yuhuangding Hospital

    Yantai, China

  • Zhejiang Cancer Hospital

    Hangzhou, China

  • Zhongshan Hospital Affiliated to Xiamen University

    Xiamen, China

  • Zhongshan Hospital Fudan University

    Shanghai, China

  • harbin medical university Cancer Hospital

    Harbin, China

Conditions

Explore the condition pages connected to this study.