New drug cocktail aims to shrink esophageal tumors before surgery

NCT ID NCT07490002

First seen Apr 11, 2026 · Last updated May 09, 2026 · Updated 2 times

Summary

This study tests whether giving three drugs (epacadostat, lenvatinib, and chemotherapy) before surgery can help eliminate or shrink esophageal cancer in 33 adults with stage II to IVa disease. The main goal is to see if the cancer completely disappears in the removed tissue. Participants must have resectable tumors and no distant spread.

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