Itching breakthrough: esketamine shot may soothe pregnancy cholestasis

NCT ID NCT07560722

First seen May 03, 2026 · Last updated May 03, 2026

Summary

This study tests whether a single injection of esketamine given during a C-section can lessen severe itching in pregnant women with intrahepatic cholestasis of pregnancy. About 160 women with moderate to severe itching will receive either esketamine or a placebo, and their itching will be measured 24 and 72 hours after surgery. The goal is to find a safe, quick way to ease this distressing symptom.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tianjin Medical University General Hospital

    Tianjin, 300052, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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