New psoriasis pill aims for clearer skin in major trial

NCT ID NCT06588738

Ongoing Disease control Sponsor: Alumis Inc Source: ClinicalTrials.gov ↗

Summary

This large, late-stage study is testing whether a daily pill called ESK-001 can safely reduce the severity of moderate-to-severe plaque psoriasis. It will compare ESK-001 against a placebo (dummy pill) and an already-approved psoriasis medication called apremilast. About 840 adults with significant, long-term psoriasis will take the study drug for 24 weeks while doctors track their skin improvement, quality of life, and any side effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Alberta DermaSurgery

Edmonton, Alberta, T6G 1C3, Canada
Allergo Derm Bakos Kft

Szolnok, 5000, Hungary
AppleMed Research Group under WCG

Miami, Florida, 33126, United States
Asheville Clinical Trials

Asheville, North Carolina, 28803, United States
Associated Skin Care Specialists - Minnesota Clinical Study Center

New Brighton, Minnesota, 55112, United States
Bacs Kiskun County Teaching Hospital

Kecskemét, Bács-Kiskun county, 6000, Hungary
Beacon Dermatology

Calgary, Alberta, T3E 0B2, Canada
Borgyogyaszati Klinika Debreceni Egyetem Orvos es Egeszsegtudomenyi Centrum

Debrecen, Hajdú-Bihar, 4032, Hungary
CCA Medical Research Corp

Ajax, Ontario, L1S 7K8, Canada
CHU de Rouen

Rouen, Normandy, 76031, France
CaRe Clinic Red Deer

Red Deer, Alberta, T4P 1K4, Canada
Cameron Dermatology

New York, New York, 10023, United States
Care Clinic Katowice

Katowice, 40-568, Poland
Center for Clinical Studies (CCS) - Webster/Clear Lake Location

Webster, Texas, 77598, United States
Center for Clinical and Basic Research AS

Tallinn, 10128, Estonia
Centre Azur Nice

Nice, 06000, France
Centro Reumatologico de Caguas

Caguas, Puerto Rico, 00725, Puerto Rico
Centrum Medyczne Evimed

Warsaw, Masovian Voivodeship, 02-625, Poland
Centrum Medyczne dr Rajzer Spolka Zoo

Krakow, Malopolska, 30-438, Poland
Chandler Clinical Trials

Chandler, Arizona, 85224, United States
Clear Skin Dermatology

Newmarket, Ontario, L3Y 5G8, Canada
Clinical Best Solutions

Warsaw, Masovian Voivodeship, 00-710, Poland
Clinical Partners LLC

Johnston, Rhode Island, 02919, United States
Clinical Research Puerto Rico

Ponce, Puerto Rico, 00909, Puerto Rico
Clinical Science Institute Dermatology Institute

Santa Monica, California, 90404, United States
DERMA B Kft

Debrecen, Hajdú-Bihar Megye, 4031, Hungary
DS Research of Kentucky

Louisville, Kentucky, 40241, United States
DS Research of Southern Indiana

Clarksville, Indiana, 47129, United States
DermResearchCenter of New York

Stony Brook, New York, 11790, United States
DermaMed Research Kf

Békés, Oroshaza, 5900, Hungary
Dermatologische Praxis Dres Quist

Mainz, Rhinelkand-Palatinate, 55128, Germany
Dermatology Research Associates

Los Angeles, California, 90045, United States
Dermoklinika

Lodz, Łódź Voivodeship, 90-436, Poland
Direct Helpers Research Center (DHRC)

Hialeah, Florida, 33012, United States
Empire Clinical Research - Pomona

Pomona, California, 91767, United States
FAX Pharma Clinical Research Inc

Miami, Florida, 33146, United States
FXM Clinical Research - Miami LLC

Miami, Florida, 33175, United States
FXM Clinical Research Ft. Lauderdale LLC

Fort Lauderdale, Florida, 33308, United States
FXM Clinical Research Miramar LLC

Miramar, Florida, 33027, United States
FutureMeds Krakow

Krakow, Lesser Poland Voivodeship, 31-501, Poland
FutureMeds Lodz

Lodz, Łódź Voivodeship, 91-363, Poland
GCM Medical Group PSC Hato Rey Site

San Juan, PR, 00917, Puerto Rico
Grekin Skin Institute

Warren, Michigan, 48088, United States
Guelph Dermatology Research

Guelph, Ontario, N1L 0B3, Canada
Haut Ambulatorium Magdeburg

Magdeburg, 39104, Germany
Hautarztpraxis Dr Niesmann and Dr Othlinghaus

Bochum, North Rhine-Westphalia, 44793, Germany
Henry Ford Medical Center - Farmington Road

Detroit, Michigan, 48202, United States
Hospital Clínico Universitario de Santiago de Compostela

Santiago de Compostela, A Coruña, 15706, Spain
Hospital Universitario 12 de Octubre

Madrid, Madrid, 28041, Spain
Hospital Universitario Virgen Macarena

Seville, 41009, Spain
Hospital de Manises

Manises, 46940, Spain
Hospital de la Santa Creu i Sant Pau

Barcelona, Barcelona, 8041, Spain
ISA - Interdisciplinary Study Association GmbH

Berlin, State of Berlin, 10789, Germany
Innomedica

Tallinn, Harju, 10117, Estonia
Innovaderm

Montreal, Quebec, H2X 2V1, Canada
Integrative Skin Science and Research

Sacramento, California, 95815, United States
Jordan Valley Dermatology

South Jordan, Utah, 84095, United States
KliFOs Klinische Forschung Osnabruck

Osnabrück, 49074, Germany
Kliiniliste Uuringute Keskus OU

Tartu, 50106, Estonia
Klinik Hietzing

Vienna, Vienna, 1220, Austria
Klinika Ambroziak Dermatologia Kliniczna

Warsaw, 02-953, Poland
Klinika Dermatologii Uniwersytecki Szpital Kliniczny im F Chopina

Rzeszów, Podkarpackie Voivodeship, 50-368, Poland
Klinikum Oldenburg

Oldenburg, Lower Saxony, 26133, Germany
Klinische Forschung Dresden GmbH

Dresden, Saxony, 1069, Germany
Klinische Forschung Schwerin GmbH

Schwerin, Mecklenburg-Vorpommern, 19055, Germany
Las Mercedes Medical Research

Miami, Florida, 33196, United States
Las Vegas Clinical Trials

Las Vegas, Nevada, 89030, United States
Long Beach Research Institute

Long Beach, California, 90805, United States
Luxderm

Lublin, Lublin Voivodeship, 20-573, Poland
MTZ Clinical Research Sp z o o

Warsaw, 02-172, Poland
MVZ DermaKiel GmbH

Kiel, D-24148, Germany
Med Art Clinic

Riga, LV1003, Latvia
Mediprobe Research

London, Ontario, N5X 2P1, Canada
Medmare Bt

Veszprém, 8200, Hungary
Michigan Center for Research Company

Clarkston, Michigan, 48346, United States
Modern Research Associates PLLC

Dallas, Texas, 75231, United States
NYC Health and Hospitals Elmhurst

Elmhurst, New York, 11373, United States
Noble Clinical Research

Tucson, Arizona, 85704, United States
North Bay Dermatology Centre

North Bay, Ontario, P1B 3Z7, Canada
Optima Research Boardman

Boardman, Ohio, 44512, United States
Orvostudomanyi Kutato es Fejleszto Kft

Debrecen, 4027, Hungary
Pioneer Clinical Research NY

New York, New York, 10016, United States
Polyclinique de Courlancy

Reims, 51100, France
Ponce Medical School Foundation Inc

Ponce, Puerto Rico, 00716, Puerto Rico
Pratia Gdynia

Gdynia, Pomeranian Voivodeship, 81-338, Poland
Pratia Katowice

Katowice, Silesian Voivodeship, 40-018, Poland
Praxis fur Dermatologie und Venerologie

Dresden, Saxony, 01097, Germany
Progressive Clinical Research - San Antonio

San Antonio, Texas, 78213, United States
RCMed Oddział Sochaczew

Sochaczew, Masovian Voivodeship, 96-500, Poland
Raoof MD

Encino, California, 91436, United States
Rejuvination Dermatology Oakville

Oakville, Ontario, L6H 6P8, Canada
Renstar Medical Research

Ocala, Florida, 34470, United States
Research Solutions

Katowice, Silesian Voivodeship, 40-748, Poland
Revival Research Institute

Troy, Michigan, 48084, United States
Riga 1st Hospital

Riga, LV1001, Latvia
Rosenpark Research

Darmstadt, Hesse, 64283, Germany
SIA Veseliba un estetika

Riga, LV1009, Latvia
SKiN Health

Cobourg, Ontario, K9A 0Z4, Canada
SMS Clinical Research

Mesquite, Texas, 75149, United States
Schlessinger MD

Omaha, Nebraska, 68144, United States
Semigallia Ltd

Kuldīga, Kuldigas, LV3301, Latvia
Sheba Tel HaShomer Medical Centre

Ramat Gan, 526200, Israel
SimcoDerm Medical and Surgical Dermatology Center

Barrie, Ontario, L4M 7G1, Canada
SkinSense Medical Research

Saskatoon, Saskatchewan, S7K 2C1, Canada
Skincare Studio

St. John's, Newfoundland and Labrador, A1E 1V4, Canada
Smite Aija Medical Practice in Dermatology Venereology

Talsi, Talsi, LV3201, Latvia
Southern California Clinical Research

Santa Ana, California, 92701, United States
Specderm

Bialystok, Podlaskie Voivodeship, 15-375, Poland
Tartu University Hospital

Tartu, Tartu, 50411, Estonia
The Indiana Clinical Trials Center

Plainfield, Indiana, 46168, United States
Toronto Research Centre

Toronto, Ontario, M3H 5Y8, Canada
Total Skin and Beauty Dermatology Center, PC

Birmingham, Alabama, 35203, United States
UC San Diego

San Diego, California, 92122, United States
Universitaetsklinikum Muenster

Münster, North Rhine-Westphalia, 48149, Germany
Universitatsklinikum Erlangen

Erlangen, Bavaria, 91054, Germany
University General Hospital Dr Balmis

Alicante, Alicante, 3010, Spain
Uno Medical Trials Kft

Budapest, 1152, Hungary
VIDA Dermatology/VIDA Clinical Research

Edmonton, Alberta, T6H 4J8, Canada
Veselibas Centrs 4

Riga, LV1003, Latvia
Veselibas Centrs 4 Filiale Dermatologijas Klinika

Riga, LV1013, Latvia
WDC Cosmetic and Research

Wilmington, North Carolina, 28405, United States
XLR8 Medical Research

Windsor, Ontario, N8T 1E6, Canada
Zanamed Medical Clinic Sp z o o

Lublin, 20-601, Poland
Zenith Research Inc.

Beverly Hills, California, 90211-1705, United States
dermMedica

Wroclaw, 51-503, Poland

Conditions

Explore the condition pages connected to this study.

PLAQUE PSORIASIS