New patch could ease bruise pain without pills

NCT ID NCT06871046

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a medicated patch containing esflurbiprofen, a pain reliever, for treating pain from bruises (contusions). 221 adults with fresh bruises on their arms or legs wore the patch for 7 days. The main goal was to check safety, and researchers also measured how well it reduced pain during movement and at rest.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
esflurbiprofen topical patch
What this could lead to
If it works, this could provide a convenient, non-oral pain relief option for bruises.
What could go wrong
This is a completed phase 3 trial, but results are not yet published. The patch may not be more effective than existing treatments, and skin irritation is a possible side effect.

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Conditions

The condition(s) this trial relates to.

Athletic Injuries Contusions Soft Tissue Injuries Wounds, Nonpenetrating

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medical Practice Ebert

    Siemensstr, Bonn, 53121, Germany

  • Medical Practice Gastl

    Römerstraße, Gilching, 82205, Germany

  • Medical Practice Pabst

    Sportschule Puch, Fürstenfeldbruck, 82556, Germany

  • Medical Practice Prof. Predel

    Siemensstr, Bonn, 53121, Germany

  • Medical Practice Schaale-Maas

    Siemensstr, Bonn, 53121, Germany

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