Which injection cuts bleeding best in fibroid surgery? new trial aims to find out

NCT ID NCT07390864

First seen Feb 05, 2026 · Last updated Jun 23, 2026 · Updated 22 times

Summary

This study tests two drugs, ergometrine and carbetocin, both injected into the uterus during surgery to remove fibroids. The goal is to see which one reduces blood loss more effectively. Forty women having abdominal myomectomy will be randomly assigned to receive one of the drugs, and their blood loss will be measured during and after surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fayoum University

    RECRUITING

    Al Fayyum, Faiyum Governorate, 38521, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Methylergometrine and Carbetocin (drugs injected into the uterus to reduce bleeding)

What this could lead to

If this trial succeeds, it could show that one of these drugs is better at reducing blood loss during fibroid surgery, potentially leading to safer procedures and fewer blood transfusions.

What could go wrong

This is a small, early-stage trial with only 40 participants, so results may not apply to all women. The drugs may not differ significantly in effectiveness, and side effects are possible.

Conditions

The condition(s) this trial relates to.

Hemorrhage myofibroma uterine corpus leiomyoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.