New hope for rare brain cancer: targeted pill shrinks tumors in early trial

NCT ID NCT05859334

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 32 times

Summary

This study tests a drug called erdafitinib in people with a specific type of brain tumor (glioma) that has come back or is growing. The drug targets a faulty protein that helps the tumor grow. About 30 adults will take the pill to see if it can shrink or slow the tumor.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hackensack University Medical Center

    RECRUITING

    Hackensack, New Jersey, 07601, United States

    Contact

    Contact Phone: •••-•••-••••

  • Huntsman Cancer Institute/University of Utah

    RECRUITING

    Salt Lake City, Utah, 84112, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Laura and Isaac Perlmutter Cancer Center at NYU Langone

    RECRUITING

    New York, New York, 10016, United States

    Contact

    Contact Email: •••••@•••••

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Memorial Hospital East

    RECRUITING

    Shiloh, Illinois, 62269, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Memorial Sloan Kettering Basking Ridge

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

    Contact Phone: •••-•••-••••

    Contact

  • Memorial Sloan Kettering Bergen

    RECRUITING

    Montvale, New Jersey, 07645, United States

    Contact Phone: •••-•••-••••

    Contact

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

    Contact

  • Memorial Sloan Kettering Commack

    RECRUITING

    Commack, New York, 11725, United States

    Contact Phone: •••-•••-••••

    Contact

  • Memorial Sloan Kettering Monmouth

    RECRUITING

    Middletown, New Jersey, 07748, United States

    Contact Phone: •••-•••-••••

    Contact

  • Memorial Sloan Kettering Nassau

    RECRUITING

    Uniondale, New York, 11553, United States

    Contact Phone: •••-•••-••••

    Contact

  • Memorial Sloan Kettering Westchester

    RECRUITING

    Harrison, New York, 10604, United States

    Contact Phone: •••-•••-••••

    Contact

  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center

    RECRUITING

    New York, New York, 10032, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Siteman Cancer Center at Christian Hospital

    RECRUITING

    St Louis, Missouri, 63136, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Siteman Cancer Center at Saint Peters Hospital

    RECRUITING

    City of Saint Peters, Missouri, 63376, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Siteman Cancer Center at West County Hospital

    RECRUITING

    Creve Coeur, Missouri, 63141, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Siteman Cancer Center-South County

    RECRUITING

    St Louis, Missouri, 63129, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCHealth University of Colorado Hospital

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact

    Contact Phone: •••-•••-••••

  • UM Sylvester Comprehensive Cancer Center at Coral Gables

    RECRUITING

    Coral Gables, Florida, 33146, United States

    Contact

    Contact Phone: •••-•••-••••

  • UM Sylvester Comprehensive Cancer Center at Deerfield Beach

    RECRUITING

    Deerfield Beach, Florida, 33442, United States

    Contact

    Contact Phone: •••-•••-••••

  • UT Southwestern/Simmons Cancer Center-Dallas

    ACTIVE_NOT_RECRUITING

    Dallas, Texas, 75390, United States

  • University of Miami Miller School of Medicine-Sylvester Cancer Center

    RECRUITING

    Miami, Florida, 33136, United States

    Contact

    Contact Phone: •••-•••-••••

  • University of Oklahoma Health Sciences Center

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center

    RECRUITING

    Madison, Wisconsin, 53718, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Wisconsin Carbone Cancer Center - University Hospital

    RECRUITING

    Madison, Wisconsin, 53792, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Wake Forest University Health Sciences

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

    Contact

    Contact Phone: •••-•••-••••

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.