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Can a structured recovery program help older knee replacement patients bounce back faster?

NCT ID NCT07828418

Symptom relief Sponsor: China Medical University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 18, 2026 · Last updated Sep 21, 2026 · Updated 1 time

Summary

Researchers are studying whether a structured Enhanced Recovery After Surgery (ERAS) care pathway improves pain, knee function, and physical resilience in adults aged 65 and older who have total knee replacement. The ERAS pathway includes preoperative assessment and education, nutritional checks, multimodal pain management, keeping patients warm during surgery, early eating and walking, and early rehabilitation. Participants receive either the ERAS pathway or the hospital's usual perioperative care. The study measures pain, knee function, and physical resilience before surgery and at several points afterward, along with vital signs, hospital stay length, and time to first walking.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Enhanced Recovery After Surgery (ERAS) care pathway, a structured program of preoperative assessment, pain control, early eating and walking, and rehabilitation
What this could lead to
If the ERAS pathway helps, it could become a standard way to speed recovery and reduce pain for older adults having knee replacement surgery.
What could go wrong
This is a small study of 60 people at one hospital, so results may not apply broadly. Recovery can vary widely between individuals, and the ERAS approach may not outperform usual care for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 65 years or older * Scheduled to undergo primary unilateral elective total knee arthroplasty (TKA) * Conscious and able to communicate in Mandarin Chinese or Taiwanese * Willing to complete the study questionnaires and provide written informed consent Exclusion Criteria: * Cognitive impairment (e.g., moderate or severe dementia) or psychiatric illness that prevents adequate understanding, communication, or study participation * Postoperative transfer to an intensive care unit, repeat surgery, or death * Withdrawal of willingness to continue study participation during the study period

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Conditions

The condition(s) this trial relates to.

Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Total knee arthroplasty (replacement)

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.