Could a common drug keep bladder cancer away?

NCT ID NCT04375813

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase II trial tests whether a low-dose version of the drug rapamycin, called eRapa, can prevent bladder cancer from coming back in people who have already been treated for non-muscle invasive bladder cancer. About 166 participants will take eRapa or a placebo daily for one year. Researchers will track cancer recurrence, quality of life, and physical and mental function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

encapsulated rapamycin (eRapa)

What this could lead to

If it works, this could offer a new way to prevent bladder cancer from coming back, reducing the need for repeated surgeries or treatments.

What could go wrong

This is a mid-stage trial with 166 participants, so results may not apply to everyone. The drug may not improve recurrence rates, and side effects like immune suppression are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-invasive bladder urothelial carcinoma Non-Muscle Invasive Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UT Health San Antonio

    San Antonio, Texas, 78229, United States

  • UT Southwestern Medical Center

    Dallas, Texas, 75390, United States