New pill aims to let patients step into the sun without pain
NCT ID NCT06144840
Summary
This study is testing whether an investigational drug called MT-7117 can help people with rare light-sensitive skin disorders (EPP or XLP) spend more time in sunlight before feeling painful burning or itching. About 165 participants, aged 12 to 75, will take either the drug or a placebo pill for 16 weeks to see if it delays and reduces these painful reactions. The main goal is to see if the drug improves patients' ability to tolerate sunlight and their overall quality of life.
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Contacts and locations
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Locations
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Assistance Publique-Hopitaux de Paris (AP-HP) - Hopital Louis-Mourier
Paris, 92701, France
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Azienda Ospedaliera Spedali Civili di Brescia-Universita degli Studi Di Brescia
Brescia, 25123, Italy
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Azienda Sanitaria Ospedaliera Santa Croce E Carle - Cuneo
Cuneo, 12100, Italy
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CHU Nantes
Nantes, 44000, France
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Centre Hospitalier Universitaire de Bordeaux - Hopital Saint - Andre
Bordeaux, 33000, France
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Einstein Medical Center (EMC)
Philadelphia, Pennsylvania, 19141, United States
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Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico di Milano
Milan, 20122, Italy
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Guy's Hospital
London, SE1 9RT, United Kingdom
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Hamamatsu University Hospital
Hamamatsu, Shizuoka, 431-3194, Japan
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Henry Ford Health System
Detroit, Michigan, 48202, United States
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Hospital General Universitario De Valencia
Valencia, 46014, Spain
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Hospital Universitario 12 de Octubre
Madrid, 28041, Spain
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Hôpital Bichat - Hospital Bichat-Hopitaux Universitaires Paris Nord Val de Seine
Paris, 75018, France
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IFO-San Gallicano IRCCS
Rome, 00144, Italy
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Icahn School of Medicine at Mount Sinai (ISMMS) - The Mount Sinai Hospital (MSH)
New York, New York, 10029-0311, United States
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Institute for Clinical and Experimental Medicine - IKEM
Prague, 01958, Czechia
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Instytut Hematologii I Transfuzjologii
Warsaw, 02-776, Poland
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Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Materno-Infantile - Burlo Garofolo - Clinica Pediatrica
Trieste, 34137, Italy
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Kansas City Research Institute
Kansas City, Missouri, 64131, United States
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MGH
Boston, Massachusetts, 02129, United States
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Marvel Clinical Research, LLC
Huntington Beach, California, 92647, United States
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Mazda Hospital
Aki-gun, Hiroshima, 735-8585, Japan
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MetroBoston Clinical Partners, LLC
Brighton, Massachusetts, 02135-3511, United States
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Ospedalle Galliera
Genova, 16128, Italy
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Remington-Davis Clinical Research
Columbus, Ohio, 43215, United States
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Royal Melbourne Hospital (RMH)
Parkville, Victoria, 03050, Australia
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Southampton General Hospital - University Hospital Southampton NHS Foundation Trust
Southamption, Southamption, SO16 6YD, United Kingdom
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The University of Texas Medical Branch (UTMB)
Galveston, Texas, 77555-0342, United States
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Tokyo Saiseikai Central Hospital
Tokyo, 108-0073, Japan
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U.O.C. Medicina Interna Azienda ospedaliero Universitaria Policlinico di Modena
Modena, 41124, Italy
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Universitair Medisch Centrum Rotterdam
Rotterdam, 03015, Netherlands
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University Multi-Profile Hospital for Active Treatment (UMHAT) St. Ivan Rilski - Porphyria Center
Sofia, 01000, Bulgaria
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University Of Miami School Of Medicine, Center For Liver Diseases
Miami, Florida, 33136, United States
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University of California at San Francisco
San Francisco, California, 94143, United States
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University of Washington
Seattle, Washington, 98195, United States
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Wake Forest University Baptist Health
Winston-Salem, North Carolina, 27103, United States
Conditions
Explore the condition pages connected to this study.