A common drug may prevent Anesthesia-Induced low blood pressure in High-Risk surgery patients
NCT ID NCT07722013
First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This trial tests whether giving small, repeated doses of ephedrine during anesthesia induction can prevent dangerously low blood pressure in patients over 50 undergoing major abdominal surgery. Participants will receive either ephedrine or a placebo (saline) every five minutes for 20 minutes after anesthesia begins. The goal is to see if this simple preventive strategy reduces the need for emergency blood pressure support.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ephedrine given as intermittent boluses during anesthesia induction
- What this could lead to
- If effective, this simple preventive approach could reduce complications from low blood pressure during surgery in older or frail patients.
- What could go wrong
- This is a single-center trial with 124 participants, so results may not apply broadly. Ephedrine can raise heart rate and blood pressure, which may be risky for some patients.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Kasr Alainy Hospital
Cairo, 11562, Egypt
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