New antibody therapy tested for Tough-to-Treat blood cancers

NCT ID NCT03625037

Summary

This trial is testing a new antibody drug called epcoritamab in people with B-cell lymphoma that has come back or stopped responding to standard treatments. The main goals are to find the safest and most effective dose, understand the side effects, and see how well the drug works to control the cancer. All 666 participants will receive the active drug, with no one getting a placebo.

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Contacts and locations

Locations

  • Akademiska sjukhuset Uppsala University Hospital

    Uppsala, Sweden

  • Ao Ss Antonio E Biagio Alessandria

    Alessandria, Italy

  • Arizona Mayo Clinic

    Phoenix, Arizona, 85054, United States

  • Asan Medical Center

    Seoul, South Korea

  • Barbara Ann Karmanos Cancer Institute

    Detroit, Michigan, 48334, United States

  • CHU Montpellier

    Montpellier, France

  • CHU de Tours-Hopital Bretonneau

    Tours, France

  • Cabrini Hospital

    Malvern, Australia

  • Centre Henri Becquerel

    Rouen, France

  • Charite - Universitaetsmedizin Berlin

    Berlin, Germany

  • Chonbuk National University Hospital

    Jeonju, South Korea

  • Clinica Universidad de Navarra

    Pamplona, Navarre, 31008, Spain

  • Colorado Blood Cancer Institute

    Denver, Colorado, 80218, United States

  • Concord Hospital

    Concord, Australia

  • Der Universität Munchen Medizinische Klinik III LMU

    München, Germany

  • Dong-A University Hospital

    Busan, South Korea

  • Erasmus MC Cancer Institute

    Rotterdam, Netherlands

  • Gold Coast Hospital

    Southport, Australia

  • H. Lee Moffitt Cancer Center and Research Institute

    Tampa, Florida, 33612, United States

  • Hackensack Meridian Health

    Hackensack, New Jersey, 07601, United States

  • Helsinki University Hospital

    Helsinki, Finland

  • Hillman Cancer Center

    Pittsburgh, Pennsylvania, 15232, United States

  • Hopital Henri Mondor

    Créteil, France

  • Hospices Civils de Lyon Centre Hospitalier Lyon Sud

    Pierre-Bénite, France

  • Hospital Germans Trias i Pujol

    Badalona, Spain

  • Hospital Saint-Louis

    Paris, France

  • Hospital Universitario Fundacin Jimnez Daz

    Madrid, Spain

  • Hospital Universitario Vall dHebron

    Barcelona, Spain

  • IRCCS Ospedale San Raffaele

    Milan, Italy

  • Institut Catala de Oncologia

    Barcelona, Spain

  • Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori

    Meldola, Italy

  • Istituto di Candiolo- Fondazione del Piemonte per l'Oncologia

    Candiolo, Italy

  • Johannes Gutenberg University

    Mainz, Germany

  • Karolinska University Hospital Huddinge

    Stockholm, Sweden

  • Keimyung University Dongsan Medical Center

    Daegu, South Korea

  • Klinik fur Innere Medizin Hamatologie and Onkologie

    Berlin, Germany

  • Kuopio University Hospital

    Kuopio, Finland

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Maastricht University Medical Center

    Maastricht, 6229 HX, Netherlands

  • Maria Sklodowska-Curie Memorial Cancer Center and Institute

    Warsaw, Poland

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Monash Health

    Clayton, Australia

  • National Cancer Center

    Goyang-si, South Korea

  • National University Hospital

    Singapore, Singapore

  • OHSU Knight Cancer Institute

    Portland, Oregon, 97210, United States

  • Ochsner Medical Center

    New Orleans, Louisiana, 70121, United States

  • Odense University Hospital

    Odense, 5000 C, Denmark

  • Plymouth University School of Medicine- Derriford Hospital

    Plymouth, United Kingdom

  • Policlinico S. Orsola-Ematologia LA Seragnoli

    Bologna, Italy

  • Pratia-McM

    Krakow, Poland

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • Rigshospitalet

    Copenhagen, Denmark

  • Royal Brisbane and Women's Hospital

    Herston, Australia

  • Royal Hobart Hospital RHH

    Hobart, Australia

  • Royal Marsden NHS Foundation Trust

    Sutton, United Kingdom

  • Samsung Medical Center

    Seoul, South Korea

  • Seoul National University Bundang Hospital

    Seongnam-si, South Korea

  • Seoul National University Hospital

    Seoul, South Korea

  • Severance Hospital, Yonsei University

    Seoul, South Korea

  • Singapore General Hospital

    Singapore, Singapore

  • Sir Charles Gairdner Hospital

    Nedlands, Australia

  • Skåne University Hospital

    Lund, Sweden

  • St. George Hospital

    Kogarah, Australia

  • St. Vincent Hospital

    Fitzroy, Australia

  • Szpital Uniwersytecki nr 2 im dr. Jana Biziela

    Bydgoszcz, Poland

  • Tampere University Hospital

    Tampere, Finland

  • The Christie NHS Foundation Trust

    Manchester, United Kingdom

  • The Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

  • Tom Baker Cancer Care

    Calgary, Canada

  • Toronto-Sunnybrook Regional Cancer Ctr

    Toronto, Canada

  • UT Southwestern

    Dallas, Texas, 75390, United States

  • Universitaetsklinikum Essen

    Essen, Germany

  • Universitaetsklinikum Koeln

    Cologne, Germany

  • Universitair Medisch Centrum Utrecht

    Utrecht, Netherlands

  • University Hospital Southampton NHS Foundation Trust

    Southampton, United Kingdom

  • University of California at San Francisco

    San Francisco, California, 94117, United States

  • University of Iowa Hospital and Clinics

    Iowa City, Iowa, 52242, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

  • Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego

    Wroclaw, Poland

  • Uniwersyteckie Centrum Kliniczne

    Gdansk, Poland

  • VU University Medical Center

    Amsterdam, Netherlands

  • Vejle Hospital

    Vejle, Denmark

  • Westmead Hospital

    Sydney, Australia

  • Wojewodzki Szpital Specjalistyczny im. Janusza Korczaka

    Słupsk, Poland

Conditions

Explore the condition pages connected to this study.