New drug combo shows promise for aggressive lymphoma

NCT ID NCT07662928

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests whether adding the drug epcoritamab to standard chemotherapy (DA-EPOCH-R) helps people with high-risk Burkitt lymphoma. About 43 adults will receive the combination. The study will check how many complete at least three cycles of treatment and track overall survival and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

epcoritamab plus chemotherapy (DA-EPOCH-R)

What this could lead to

If it works, this could offer a more effective treatment option for people with high-risk Burkitt lymphoma, potentially improving survival rates.

What could go wrong

This is an early phase 2 trial with only 43 participants, so results may not apply to everyone. The combination may cause serious side effects, and it's not yet known if it works better than standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Burkitt lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10021, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••