New drug combo aims to boost lymphoma treatment

NCT ID NCT07588698

First seen May 17, 2026 · Last updated Jun 17, 2026 · Updated 5 times

Summary

This study tests a new drug, epcoritamab, added to standard chemotherapy (R-CHOP) for people newly diagnosed with aggressive B-cell lymphoma. The main goal is to check safety, especially a side effect called cytokine release syndrome. About 20 adults will join this early-phase trial to see if the combination is safe enough for larger studies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California, San Francisco

    San Francisco, California, 94143, United States

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Zuckerberg San Francisco General

    San Francisco, California, 94110, United States

    Contact Phone: •••-•••-••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

B-cell neoplasm B-cell non-Hodgkin lymphoma diffuse large B-cell lymphoma Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly follicular lymphoma high grade B-cell lymphoma with MYC and/ or BCL2 and/or BCL6 rearrangement lymphoma, non-Hodgkin, familial non-Hodgkin lymphoma primary mediastinal large B-cell lymphoma T-cell/histiocyte rich large B cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.