New drug combo aims to outsmart tough lymphoma

NCT ID NCT06536049

First seen Feb 20, 2026 · Last updated May 08, 2026 · Updated 11 times

Summary

This study is for people with aggressive B-cell non-Hodgkin lymphoma that has returned or not responded to previous treatments. It tests a combination of two drugs: epcoritamab, which helps the immune system attack cancer cells, and ibrutinib, which blocks signals that help cancer cells grow. The goal is to find the safest dose and see if the combination can shrink or control the cancer. About 38 adults will take part.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Minnesota/Masonic Cancer Center

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

    Contact Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.