New hope for hard-to-treat brain cancer: combo therapy enters phase 2 trial

NCT ID NCT06931652

First seen Feb 15, 2026 · Last updated May 15, 2026 · Updated 18 times

Summary

This study tests a new drug called epcoritamab, given with two other drugs (lenalidomide and rituximab), for people whose primary CNS lymphoma has returned or not responded to prior treatment. About 60 adults will take part to see if the combination can shrink tumors and how safe it is. The goal is to control the disease, not cure it, as ongoing management is expected.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHR DE MARSEILLE - CHU TIMONE - Service de Neuro-Oncologie

    ACTIVE_NOT_RECRUITING

    Marseille, France

  • CHRU DE NANCY - HOPITAL CENTRAL - Service de Neurologie

    ACTIVE_NOT_RECRUITING

    Nancy, France

  • CHU BRETONNEAU - Service Cancérologie - Hématologie et Thérapie Cellulaire

    ACTIVE_NOT_RECRUITING

    Tours, France

  • CHU DE LILLE - HOPITAL CLAUDE HURIEZ - Service des Maladies du Sang

    RECRUITING

    Lille, France

    Contact

  • CHU ESTAING - Service Thérapie Cellulaire et Hématologie Clinique

    RECRUITING

    Clermont-Ferrand, France

    Contact

  • CHU LYON-SUD - Hématologie Clinique

    RECRUITING

    Pierre-Bénite, France

    Contact

  • CHU PONTCHAILLOU - Hématologie Clinique

    NOT_YET_RECRUITING

    Rennes, France

    Contact

  • GHU PITIE-SALPETRIERE - CHARLES FOIX - Service Neurologie

    ACTIVE_NOT_RECRUITING

    Paris, France

  • HOPITAL DE LA PITIE SALPETRIERE - Service Hématologie Clinique

    ACTIVE_NOT_RECRUITING

    Paris, France

  • INSTITUT BERGONIE - Service d'Oncologie Médicale

    ACTIVE_NOT_RECRUITING

    Bordeaux, France

  • INSTITUT CURIE - SITE SAINT-CLOUD - Service Hématologie

    ACTIVE_NOT_RECRUITING

    Saint-Cloud, France

  • INSTITUT D'HEMATOLOGIE DE BASSE NORMANDIE - Service Hématologie

    RECRUITING

    Caen, France

    Contact

  • IUCT ONCOPOLE - Service Hématologie

    RECRUITING

    Toulouse, France

    Contact

Conditions

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