Experimental drug aims to tame uncontrollable hives

NCT ID NCT06077773

Summary

This study tested whether an experimental drug called EP262 could reduce symptoms in people with chronic spontaneous urticaria (long-lasting hives with no clear trigger). 113 participants who still had significant hives despite standard antihistamine treatment were randomly assigned to receive either EP262 or a placebo for 6 weeks. Researchers measured changes in daily itch severity and hive counts to see if the drug provided better relief than the dummy treatment.

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Contacts and locations

Locations

  • Advanced Clinical Research Institute

    Tampa, Florida, 33607, United States

  • AllerVie Clinical Research

    Birmingham, Alabama, 35209, United States

  • Allergy & Asthma Specialists, P.S.C.

    Owensboro, Kentucky, 42301, United States

  • Allergy Associates of Utah

    Murray, Utah, 84107, United States

  • Allergy Partners Clinical Research

    Asheville, North Carolina, 28803, United States

  • Allergy and Asthma Specialists Medical Group

    Huntington Beach, California, 92647, United States

  • Allergy and Clinical Immunology Associates

    Pittsburgh, Pennsylvania, 15241, United States

  • Allervie Clinical Research

    Destin, Florida, 32541, United States

  • Antelope Valley Clinical Trials

    Los Angeles, California, 90025, United States

  • Bernstein Clinical Research Center, LLC

    Cincinnati, Ohio, 45236, United States

  • Bobby Buka MD, PC

    New York, New York, 11211, United States

  • Centre de Recherche Saint-Louis

    Québec, Quebec, Canada

  • Centre for Human Drug Research

    Leiden, South Holland, 2333 CL, Netherlands

  • Centrum Badan Klinicznych PI-House Sp. z o.o.

    Gdansk, Pomeranian Voivodeship, 80-546, Poland

  • Chesapeake Clinical Research, Inc.

    White Marsh, Maryland, 21162, United States

  • Clinical Partners, LLC

    Johnston, Rhode Island, 02919, United States

  • Corning Center for Clinical Research

    Horseheads, New York, 14845, United States

  • Dawes Fretzin Clinical Research Group, LLC

    Indianapolis, Indiana, 46250, United States

  • Evidence Based Medical Educator Inc

    Toronto, Ontario, M5G 1E2, Canada

  • First OC Dermatology Research, Inc.

    Fountain Valley, California, 92708, United States

  • Florida Center for Allergy and Asthma Research

    Miami, Florida, 33186, United States

  • Hospital Arnau de Vilanova

    Valencia, 46015, Spain

  • Hospital Clinico San Carlos

    Madrid, 28040, Spain

  • Hospital del Mar

    Barcelona, 08003, Spain

  • Institut fur Allergieforschung Charite - Universitatsmedizin Berlin

    Berlin, 12203, Germany

  • Johns Hopkins University

    Baltimore, Maryland, 21224, United States

  • Las Vegas Clinical Trials

    North Las Vegas, Nevada, 89030, United States

  • Little Rock Allergy & Asthma Clinical Research Center

    Little Rock, Arkansas, 72205, United States

  • Medizinische Hochschule Hannover

    Hanover, Lower Saxony, 30625, Germany

  • Montana Medical Research, Inc.

    Missoula, Montana, 59808, United States

  • National Allergy and Asthma Research, LLC.

    North Charleston, South Carolina, 29420, United States

  • NuLine Clinical Trial Center

    Pompano Beach, Florida, 33060, United States

  • Pim Mswia

    Warsaw, Masovian Voivodeship, 02-507, Poland

  • Progressive Clinical Research, PA

    San Antonio, Texas, 78213, United States

  • Prywatna Praktyka Lekarska Ewa Ring

    Warsaw, Masovian Voivodeship, 02-482, Poland

  • Red Maple Trials Inc.

    Ottawa, Ontario, K1H1E4, Canada

  • Scottsdale Clinical Trials

    Scottsdale, Arizona, 85260, United States

  • Southern Indiana Clinical Trials

    New Albany, Indiana, 47150, United States

  • The Clinical Research Center LLC

    St Louis, Missouri, 63141, United States

  • The Indiana Clinical Trials Center

    Plainfield, Indiana, 46168, United States

  • Toledo Institute of Clinical Research Inc.

    Toledo, Ohio, 43617, United States

  • Treasure Valley Medical Research

    Boise, Idaho, 83706, United States

  • Universitatsmedizin Mainz der Johannes Gutenberg-Universitat

    Mainz, Rhineland-Palatinate, 55131, Germany

  • University of Miami Itch Center

    Miami, Florida, 33136, United States

  • University of South Florida

    Tampa, Florida, 33612, United States

  • Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden

    Dresden, Saxony, 01307, Germany

  • Velocity Clinical Research, Overland Park, KC Asthma & Allergy

    Overland Park, Kansas, 66210, United States

  • Vital Prospects Clinical Research Institute, PC

    Tulsa, Oklahoma, 74136, United States

Conditions

Explore the condition pages connected to this study.