Vaccine fights recurrent brain tumors in early trial

NCT ID NCT04116658

First seen Jan 06, 2026 · Last updated May 16, 2026 · Updated 16 times

Summary

This study tested a new vaccine called EO2401 in 100 adults with glioblastoma that had returned after standard treatment. The vaccine was given alone or with other drugs to see if it is safe and helps the immune system fight the cancer. The goal was to find a better way to control this aggressive brain tumor.

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Contacts and locations

Locations

  • Centre Georges François Leclerc

    Dijon, 21000, France

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Hôpital Pitié-Salpétrière

    Paris, 75013, France

  • Institit Catala D'Oncologia - Hospital Duran i Reynals

    L'Hospitalet de Llobregat, 8908, Spain

  • Klinik und Poliklinik für Neurologie Universitätsklinikum Bonn

    Bonn, 53105, Germany

  • Medizinische Fakultät Mannheim der Universität Heidelberg

    Mannheim, 68167, Germany

  • Neurologische Klinik & Nationales Zentrum für Tumorenerkrankungen Heidelberg Universitätsklinikum Heidelberg

    Heidelberg, 69120, Germany

  • Universitätsklinikum Frankfurt Goethe-Universität Dr. Senckenbergisches Institut für Neuroonkologie

    Frankfurt am Main, 60528, Germany

  • Zentrum für Neuroonkologie Universitätsklinikum Tübingen

    Tübingen, 72076, Germany

Conditions

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