New targeted drug shows promise for Hard-to-Treat lung cancer

NCT ID NCT01625234

First seen Apr 30, 2026 ยท Last updated Apr 30, 2026

Summary

This study tested a new drug called ensartinib (X-396) in 131 people with advanced solid tumors, including those with ALK-positive non-small cell lung cancer. The main goal was to find the safest dose and see if the drug could shrink tumors. Results helped guide further research on this targeted therapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope National Med Ctr

    Duarte, California, 91010, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • New York University Langone Medical Center

    New York, New York, 10016, United States

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States

  • Stanford University

    Stanford, California, 94305, United States

  • Tennessee Oncology, PLLC

    Nashville, Tennessee, 37203, United States

  • UCSD Moores Cancer Center

    La Jolla, California, 92093, United States

  • University of Southern California Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • University of Wisconsin Carbone Cancer Ctr

    Madison, Wisconsin, 53792, United States

  • Vanderbilt University

    Nashville, Tennessee, 37240, United States

  • Walter Reed National Military Medical Center

    Bethesda, Maryland, 20889, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.