New pill could ease lupus skin rashes in major trial

NCT ID NCT07355218

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a drug called enpatoran for people with lupus who have active skin rashes or lesions. About 202 participants will take either enpatoran or a placebo twice daily for 24 weeks, alongside their usual treatments. The goal is to see if the drug can significantly improve skin symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Enpatoran (a drug taken as a tablet twice daily)

What this could lead to

If it works, this could offer a new treatment option for people with lupus-related skin rashes and lesions, potentially reducing their severity.

What could go wrong

This is an early Phase 3 trial with only 202 participants, so results may not apply to everyone. The drug may not prove more effective than placebo, and side effects are still being studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cutaneous lupus erythematosus discoid lupus erythematosus systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bolanos Clinical Research

    RECRUITING

    Pembroke Pines, Florida, 33026, United States

  • Dawes Fretzin Clinical Research Group, LLC

    RECRUITING

    Indianapolis, Indiana, 46250, United States

  • Inland Rheumatology Clinical Trials, Inc.

    RECRUITING

    Upland, California, 91786, United States

  • Omega Research Debary, LLC

    RECRUITING

    DeBary, Florida, 32713, United States