New shot aims to calm diabetic foot pain

NCT ID NCT04469270

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 31 times

Summary

This study tested a medicine called Engensis to see if it can reduce pain in people with diabetic nerve damage in their feet and lower legs. 162 adults with type 1 or 2 diabetes took part. The treatment was given as a shot into the muscle and compared to a placebo (fake treatment). The goal was to measure pain changes over 6 months using a standard pain scale.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Arizona Research Center

    Phoenix, Arizona, 85053, United States

  • California Medical Clinic for Headache

    Los Angeles, California, 90048, United States

  • ClinPoint Trials LLC

    Waxahachie, Texas, 75165, United States

  • Clinical Research Professionals

    Chesterfield, Missouri, 63005, United States

  • Clinical Trials - Little Rock

    Little Rock, Arkansas, 72205, United States

  • Clinical Trials Research - Sacramento

    Sacramento, California, 95821, United States

  • Dominion Medical Associates

    Richmond, Virginia, 23219, United States

  • Eastern Virginia Medical School

    Norfolk, Virginia, 23510, United States

  • Foot & Ankle Center of Illinois

    Springfield, Illinois, 62704, United States

  • Futuro Clinical Trials, LLC

    McAllen, Texas, 78501, United States

  • Gateway Clinical Trials, LLC

    O'Fallon, Illinois, 62269, United States

  • Health Concepts

    Rapid City, South Dakota, 57702, United States

  • Innovative Research of West Florida, Inc.

    Clearwater, Florida, 33756, United States

  • Manassas Clinical Research Center

    Manassas, Virginia, 20110, United States

  • Nerve and Muscle Center of Texas

    Houston, Texas, 77030, United States

  • Richmond Behavioral Associates

    Staten Island, New York, 10314, United States

Conditions

Explore the condition pages connected to this study.