New drug shrinks tumors in Hard-to-Treat bladder cancer

NCT ID NCT04995419

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested enfortumab vedotin, a drug that delivers chemotherapy directly to cancer cells, in 40 Chinese patients with advanced bladder cancer that had worsened after standard treatments. The main goal was to see how many patients' tumors shrank. The trial also looked at how long the effect lasted and how safe the drug was. Results help determine if this drug is a good option for this patient group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

enfortumab vedotin (PADCEV)

What this could lead to

If successful, this could provide a new treatment option for Chinese patients with advanced bladder cancer who have run out of standard therapies.

What could go wrong

This is a small, early-phase study with only 40 participants. The drug may cause side effects like nerve damage or skin reactions, and not all patients responded.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bladder transitional cell carcinoma urinary bladder carcinoma urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Site CN86001

    Beijing, China

  • Site CN86002

    Guangzhou, China

  • Site CN86003

    Wuhan, China

  • Site CN86004

    Shanghai, China

  • Site CN86006

    Hangzhou, China

  • Site CN86007

    Nanjing, China

  • Site CN86009

    Changsha, China