New injection could free patients from daily calcium pills

NCT ID NCT05778071

Summary

This study is testing whether a daily injection called eneboparatide can help people with chronic hypoparathyroidism. For the first 24 weeks, 165 participants will receive either the real injection or a placebo (dummy injection), with neither patients nor doctors knowing which. The main goal is to see if the treatment allows patients to stop taking high doses of vitamin D and calcium supplements while keeping their blood calcium at normal levels.

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Contacts and locations

Locations

  • Aarhaus University Hospital

    Aarhus, 8200, Denmark

  • Academy of Diabetes, Thyroid and Endocrine

    El Paso, Texas, 79935, United States

  • Arthritis Northwest, PLLC

    Spokane, Washington, 99204, United States

  • Azienda Ospedaliera Universitaria Careggi

    Florence, 50134, Italy

  • Azienda Ospedaliera Universitaria Pisana-Ospedale di Cisanello

    Pisa, 56124, Italy

  • Azienda Ospedaliero Universitaria de Bologna, Policlinico Sant Orsola Malpighi

    Bologna, 40138, Italy

  • Bone Research and Education Center

    Oakville, Ontario, L6M 1M1, Canada

  • CHU de Nantes - Hôtel-Dieu

    Nantes, 44093, France

  • CHU de Quebec Research Centre

    Québec, G1V 4G2, Canada

  • Cendrum Zdrowi MDM - EB Group Sp.

    Warsaw, 00189, Poland

  • Centro Hospital Vila Nova de Faia/Espinho

    Porto, 4434-502, Portugal

  • Churchill Hospital

    Oxford, OX3 7LE, United Kingdom

  • Clinica Universidad de Navarra

    Pamplona, 31008, Spain

  • Colombia University Irving Medical Center

    New York, New York, 10032, United States

  • Complejo Hospitalario Universitario de A Coruna

    A Coruña, 15006, Spain

  • Denver Endocrinology Diabetes and Thyroid Center

    Denver, Colorado, 80113, United States

  • Eastern Regional Health Authority Health Sciences Centre

    St. John's, Newfoundland and Labrador, A1B 3V6, Canada

  • Eramus MC - University Medical Center

    Rotterdam, 3015 GD, Netherlands

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano

    Milan, 20122, Italy

  • Harbor UCLA Medical Center Endocrinology

    Torrance, California, 90502, United States

  • Hopital de la Conception-APHM

    Marseille, 13385, France

  • Hospital Bicetre AP-HP

    Paris, 94275, France

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario Virgen del Rocio

    Seville, 41013, Spain

  • Hospital da Luz Lisboa

    Lisbon, 1500-650, Portugal

  • Indiana University (IU) Health University Hospital

    Indianapolis, Indiana, 46202, United States

  • Instytut Centrum Zdrowia Matki Polki. Klinika Endokrynologii Chorob Metabolicznych

    Lodz, 93-338, Poland

  • Kanazawa University Hospital

    Kanazawa, Japan

  • Leiden University Medical Center

    Leiden, 2333, Netherlands

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Medicover Neuroendokrinologie MVZ

    Munich, 81667, Germany

  • Medycyny Nuklearnej i Chorob Wewnetrznych

    Krakow, 30-688, Poland

  • Norfolk & Norwich University NHS Foundation Trust, Quadrum Institute

    Norwich, NR4 7UQ, United Kingdom

  • North Shore University Health System

    Evanston, Illinois, 60201, United States

  • Northern Nevada Endocrinology

    Reno, Nevada, 89511, United States

  • Osaka City Hospital

    Osaka, Japan

  • Osaka Metropolital University Hospital

    Osaka, Japan

  • Pecsi Tudomanyegyetem

    Pécs, 7624, Hungary

  • Physician's East Endocrinology

    Greenville, North Carolina, 27834, United States

  • Rigshospitalet

    Copenhagen, Denmark

  • Semmelweis Egyetem Belgyogyaszati es Hematologiai Klinika

    Budapest, 1083, Hungary

  • Teikyo University Chiba Medical Center

    Chiba, Japan

  • The Children's Hospital of Philadelphia (CHOP)

    Philadelphia, Pennsylvania, 19104, United States

  • The Children's Hospital of Philadephia

    Philadelphia, Pennsylvania, 19104, United States

  • The Ohio State University Wexner Medical Center

    Columbus, Ohio, 43210, United States

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • Tokushima University Hospital

    Tokushima, Japan

  • Tottori University Hospital

    Tottori, Japan

  • Universitaetsklinikum Wuerzburg

    Würzburg, 97080, Germany

  • Universitatsklinikum Carl Gustav Carus an der TU Dresden

    Dresden, 01307, Germany

  • University Hospitals of Leicester NHS Trust

    Leicester, LE1 5WW, United Kingdom

  • University of Chicago - Medical Center

    Chicago, Illinois, 60637, United States

  • Via Alvaro del Portillo, 200, Roma, Italy 00128

    Roma, 00128, Italy

Conditions

Explore the condition pages connected to this study.