Can measuring donor vessel damage boost transplant success?

NCT ID NCT05609123

Recruiting now Knowledge-focused Sponsor: University Hospital Hradec Kralove Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at a thin layer inside blood vessels, called the glycocalyx, in people who have been declared brain dead and are organ donors. Researchers want to see if damage to this layer affects how well donated organs work after transplant. By understanding this, they hope to find ways to improve organ quality, especially from donors whose organs might not be ideal. The study involves 100 participants and measures certain markers in blood and urine.

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Conditions

The condition(s) this trial relates to.

Hypoxia, Brain Rejection, Psychology transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN DAMAGE DUE TO HYPOXIA ORGAN DONORS ORGAN TRANSPLANT FAILURE OR REJECTION

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

University Hospital Hradec Kralove
RECRUITING

Hradec Králové, 50005, Czechia

Contact Phone: •••-•••-•••• Email: •••••@•••••