New procedure offers hope for stomach paralysis sufferers

NCT ID NCT05039424

First seen Jan 05, 2026 · Last updated May 23, 2026 · Updated 23 times

Summary

This study tests a procedure called per-oral pyloromyotomy (POP) to see if it improves stomach emptying and reduces symptoms like nausea and vomiting in people with gastroparesis (slow stomach emptying) that hasn't gotten better with medication. About 100 adults aged 18-75 will be randomly assigned to get the real procedure or a sham (fake) procedure. The main goal is to measure changes in symptom severity and stomach emptying 12 weeks after treatment.

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Contacts and locations

Locations

  • Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

Conditions

Explore the condition pages connected to this study.