New drug combo aims to halt endometrial cancer growth

NCT ID NCT03008408

First seen Nov 21, 2025 · Last updated Apr 28, 2026 · Updated 21 times

Summary

This study tests whether adding ribociclib to the standard combination of everolimus and letrozole can better control advanced or recurrent endometrial cancer. About 90 participants will receive either the two-drug or three-drug regimen. The goal is to see if the triple therapy improves the rate of tumor shrinkage or stabilization.

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Contacts and locations

Locations

  • Lyndon Baines Johnson General Hospital

    Houston, Texas, 77026-1967, United States

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.