Lung valves could shrink Drug-Resistant TB cavities

NCT ID NCT07296055

First seen Jan 11, 2026 · Last updated May 01, 2026 · Updated 16 times

Summary

This study tests whether placing one-way valves in the lungs can shrink cavities caused by drug-resistant tuberculosis (TB) or nontuberculous mycobacteria (NTM) infections. The valves create a low-oxygen environment that may slow or stop bacterial growth. About 30 adults with cavities that cannot be surgically removed will be randomly assigned to receive either standard care or standard care plus the valve. The main goals are to see if cavities shrink by at least half and if sputum tests become negative for the bacteria after 9 months.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Azienda Ospedaliera Universitaria Careggi

    Florence, FI, 50134, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

    Contact

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