New combo targets Leukemia's genetic weakness

NCT ID NCT03683433

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 31 times

Summary

This study tests whether combining two drugs, enasidenib and azacitidine, can help people with a specific genetic form of acute myeloid leukemia (AML) that has returned or not responded to prior treatment. About 50 adults with an IDH2 gene mutation will receive the combination to see if it shrinks or clears the cancer. The goal is to improve remission rates and survival.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MYELODYSPLASTIC SYNDROME are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-••••

    Contact

Conditions

Explore the condition pages connected to this study.