New surgical technique could cut bladder cancer recurrence

NCT ID NCT05223491

Completed Disease control Sponsor: Jørgen Bjerggaard Jensen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two surgical methods for removing non-muscle invasive bladder tumors. The new method removes the tumor in one piece, while the standard method removes it in fragments. Researchers want to see if the one-piece approach leads to better tumor removal and fewer recurrences. The trial includes 220 patients with tumors between 1 and 6 cm.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: En Bloc resection procedure
What this could lead to: If successful, this surgical technique could lower the chance of bladder cancer coming back and reduce the need for repeat surgeries.
What could go wrong: This is a relatively small, early-stage trial with 220 patients. The procedure may not prove better than standard surgery, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

non-invasive bladder urothelial carcinoma Non-Muscle Invasive Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-MUSCLE INVASIVE BLADDER CANCER

Contacts and locations

Locations

Department of Urology, Aalborg University Hospital

Aalborg, 9100, Denmark
Department of Urology, Aarhus University Hospital

Aarhus, 8200, Denmark
Department of Urology, Herlev Hospital

Herlev, Denmark
Department of Urology, Odense University Hospital

Odense, 5000, Denmark
Department of Urology, Regional Hospital Gødstrup

Holstebro, 7500, Denmark
Department of Urology, Vestfold Hospital

Tønsberg, 3103, Norway
Department of Urology, Zealand University Hospital

Roskilde, 4000, Denmark
Dept. of Urology, Hospital Lilelbælt, Vejle

Vejle, 7100, Denmark
Dept. of Urology, North Estonia Medical Centre

Tallinn, 13419, Estonia
Dept. of Urology, Turku University Hospital

Turku, 20521, Finland
Urological Center, Paula Stradina Clinical University Hospital

Riga, LV-1002, Latvia

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