Chest tube drugs or surgery? new trial aims to settle best treatment for serious lung infection

NCT ID NCT04095676

Recruiting now Disease control Sponsor: Thomas Decker Christensen Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 29 times

Summary

This study compares two ways to treat pleural empyema, a serious lung infection with a 15% death rate. One group gets medication (fibrinolytics and DNase) through a chest tube, while the other has keyhole surgery (VATS). The goal is to see which approach leads to a shorter hospital stay and better recovery. About 184 adults in Denmark will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

Aarhus University Hospital
RECRUITING

Aarhus, Aarhus, 8200, Denmark

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Odense University Hospital
RECRUITING

Odense, Denmark

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Rigshospitalet
NOT_YET_RECRUITING

Copenhagen, Denmark

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Conditions

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PLEURAL EMPYEMA