Diabetes drug takes on statins in battle against fatty liver

NCT ID NCT07180745

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether empagliflozin (a diabetes drug) works better than statins for treating non-alcoholic fatty liver disease (NAFLD) and its more severe form, NASH. 400 obese, diabetic adults with NAFLD/NASH will take one of five drug combinations daily for 3 months. Researchers will measure liver fat and stiffness using a special ultrasound (FibroScan) and track side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Empagliflozin, Atorvastatin, Pioglitazone

What this could lead to

If successful, this could show that empagliflozin, alone or with statins, is a better option than statins alone for reducing liver fat and stiffness in people with NAFLD/NASH.

What could go wrong

This is a Phase 4 trial, so the drugs are already approved, but it's still early for this specific use. The 3-month treatment period is short, and results may not show lasting benefits or apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metabolic dysfunction-associated steatohepatitis metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Teaching hospital of Beni Suef University

    Banī Suwayf, 62727, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••