Could a simple shot replace IV treatments for severe bleeding disorder?

NCT ID NCT05500807

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether emicizumab (Hemlibra), a medicine given as a shot under the skin, can safely prevent bleeding in people with severe von Willebrand disease (VWD) or combined VWD/hemophilia A. About 40 participants of any age (including infants) will receive the drug and be monitored for bleeds and side effects. If successful, it could offer a more convenient alternative to current IV treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bleeding and Clotting Disorders Institute (BCDI)

    RECRUITING

    Peoria, Illinois, 61614, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Central Michigan University: Children's Hospital of Michigan

    RECRUITING

    Mount Pleasant, Michigan, 48859, United States

    Contact

    Contact Email: •••••@•••••

  • Children's Mercy Hospital

    RECRUITING

    Kansas City, Missouri, 64108, United States

    Contact Email: •••••@•••••

    Contact

  • Innovative Hematology, Inc. (IHI)

    RECRUITING

    Indianapolis, Indiana, 46260, United States

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

  • Penn State College of Medicine

    RECRUITING

    Hershey, Pennsylvania, 17033, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • St. Joseph's Children's Hospital - Center for Bleeding and Clotting Disorders

    RECRUITING

    Tampa, Florida, 33607, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • Stanford University: Stanford Children's Health

    RECRUITING

    Redwood City, California, 94063, United States

    Contact

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • The Center for Comprehensive Care and Diagnosis of Inherited Blood Disorders (CIBD)

    RECRUITING

    Orange, California, 92868, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • UW Health Comprehensive Program for Bleeding Disorders

    RECRUITING

    Madison, Wisconsin, 53792, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • University of Miami - Miller School of Medicine

    RECRUITING

    Coral Gables, Florida, 33146, United States

    Contact

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • University of Michigan Medical School

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

  • Washington Center for Bleeding Disorders

    RECRUITING

    Seattle, Washington, 98101, United States

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

hemophilia A von Willebrand disease 3

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.