Breakthrough shot slashes bleeding in hemophilia patients

NCT ID NCT03315455

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 24 times

Summary

This study tested a medicine called emicizumab in 85 people with hemophilia A, a condition that causes frequent bleeding. Participants received either weekly or monthly injections of emicizumab, or no preventive treatment. The goal was to see if emicizumab could reduce the number of bleeding episodes. Results showed that those taking emicizumab had significantly fewer bleeds compared to those who did not take it.

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Contacts and locations

Locations

  • Beijing Children's Hospital, Capital Medical University

    Beijing, 100045, China

  • Peking Union Medical College Hospital

    Beijing, 100730, China

  • Penang General Hospital

    George Town, Pulau Pinang, 10990, Malaysia

  • Prince of Wales Hospital

    Shatin, Hong Kong

  • Queen Elizabeth Hospital

    Sabah, Sabah, 88586, Malaysia

  • Queen Mary Hospital

    Hong Kong, Hong Kong

  • Ramathibodi Hospital

    Bangkok, 10400, Thailand

  • Ruijin Hospital Shanghai Jiaotong University School of Medicine

    Shanghai, 200025, China

  • Southern Medical University Nanfang Hospital

    Guangdong Province Guangzhou City, 510515, China

  • Tianjin Institute of Hematology & Blood Diseases Hospital

    Tianjin, 300020, China

  • Tongji Hosp, Tongji Med. Col, Huazhong Univ. of Sci. & Tech

    Wuhan, 430030, China

  • Xiangya Hospital of Centre-South University

    Changsha, 410008, China

  • Xiehe Hospital, Tongji Medical College Huazhong University of Science & Technology

    Wuhan, 430022, China

Conditions

Explore the condition pages connected to this study.