New hope for rheumatoid arthritis sufferers: experimental drug ELV001 enters phase 2 trial

NCT ID NCT07409103

Recruiting now Disease control Sponsor: Elevara Medicines Limited Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 21, 2026 · Updated 2 times

Summary

This study tests an experimental drug called ELV001 in people with active rheumatoid arthritis who have not gotten enough relief from standard treatments like methotrexate or TNF inhibitors. About 180 to 220 adults will receive either ELV001 or a placebo added to their current medication. The main goal is to see if ELV001 reduces disease activity over 12 weeks, while also checking for side effects.

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Conditions

The condition(s) this trial relates to.

rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACTIVE RHEUMATOID ARTHRITIS

Contacts and locations

Locations

Accurate Clinical Management, LLC. - Accurate Clinical Research Inc (SMO/ Network)
RECRUITING

Baytown, Texas, 77521, United States
Accurate Clinical Research Inc (SMO/ Network)
RECRUITING

Lake Charles, Louisiana, 70605, United States
Accurate Clinical Research Inc (SMO/ Network)
RECRUITING

Houston, Texas, 77089, United States
Altoona Arthritis & Osteoporosis Center
RECRUITING

Duncansville, Pennsylvania, 16635, United States
Arizona Arthritis & Rheumatology Associates
RECRUITING

Gilbert, Arizona, 85032, United States
Arizona Arthritis & Rheumatology Associates
RECRUITING

Glendale, Arizona, 85306, United States
Arizona Arthritis & Rheumatology Associates
RECRUITING

Tucson, Arizona, 85704, United States
Bioresearch Partner - Cliniverse Research (Network)
RECRUITING

South Miami, Florida, 33143, United States
CRISMO Research Centre - Bertha Gxowa Hospital
RECRUITING

Germiston, Gauteng, 1401, South Africa
Carolina Arthritis Associates - Cliniverse Research (Network)
RECRUITING

Wilmington, North Carolina, 28401, United States
Clinical Research Unit, University of Pretoria, Room 2-54, Pathology Building, Prinshof Medical Campus Dr. Savage Road, incorporating Steve Biko Hospital, Steve Biko Road
RECRUITING

Pretoria, Gauteng, 0002, South Africa
DJL Clinical Research PLLC (Network) cIRB
RECRUITING

Charlotte, North Carolina, 28262, United States
DM Clinical Research (Network)
RECRUITING

Tomball, Texas, 77375, United States
DM Clinical Research (Network)
RECRUITING

Tomball, Texas, 77377, United States
Denver Arthritis Clinic
RECRUITING

Denver, Colorado, 80230, United States
Epic Medical Research-Red Oak
RECRUITING

Red Oak, Texas, 78666, United States
Floridian Clinical Research, LLC - Clinitiative Health Research (Network)
RECRUITING

Miami Beach, Florida, 33016, United States
Great Lakes Center of Rheumatology
RECRUITING

Lansing, Michigan, 48911, United States
Heights Rheumatology and Aesthetics - ES Clinical Research Group Network
RECRUITING

Jackson, Texas, 11372, United States
Millennium Medical Research LLC - Clinitiative Health Research (Network)
RECRUITING

Miami, Florida, 33126, United States
Netcare Jakaranda Hospital Suite 102
RECRUITING

Pretoria, Gauteng, 0002, South Africa
Netcare Umhlanga Medical Centre
RECRUITING

Durban, KwaZulu-Natal, 4319, South Africa
Panorama Medical Center
RECRUITING

Panorama, Cape Town, 7500, South Africa
Pennsylvania Regional Center for Arthritis & Osteoporosis Research
RECRUITING

Wyomissing, Pennsylvania, 19610, United States
Prophase, LLC - Clinitiative Health Research (Network)
RECRUITING

Margate, Florida, 33063, United States
Rheumatology Associates of South Florida-Clinical Research Inc - Cliniverse Research (Network)
RECRUITING

Boca Raton, Florida, 33486, United States
Solace Clinical Research - Populace Health (Network)
RECRUITING

Tustin, California, 92780, United States
The Arthritis Clinical Trial Centre
RECRUITING

Pinelands, Capetown, 7405, South Africa
Winelands Medical Research Centre
RECRUITING

Stellenbosch, Western Cape, 7600, South Africa
Winelands Medical Research Centre - Somerset West (Dr Francois Bouwer INC)
RECRUITING

Somerset West, Capetown, 7500, South Africa