New hope for Hard-to-Treat myeloma: drug combo targets resistant cancer

NCT ID NCT05981209

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 33 times

Summary

This early-phase trial tests a combination of three drugs (elotuzumab, mezigdomide, and dexamethasone) in 12 adults with multiple myeloma that has come back or stopped responding after prior treatments. The goal is to find a safe dose and see if the combination can control the cancer. Participants must have tried at least two other treatments first.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

Conditions

Explore the condition pages connected to this study.