New hope for elderly colorectal cancer patients: triple therapy shows promise
NCT ID NCT03451370
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how well a combination of three drugs—capecitabine, oxaliplatin, and bevacizumab—works as a first treatment for elderly patients (70 and older) with metastatic colorectal cancer that cannot be removed by surgery. The goal is to see if this approach can delay cancer growth in real-world practice. The study enrolled 121 participants and is no longer recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- capecitabine, oxaliplatin, and bevacizumab
- What this could lead to
- If successful, this could confirm a safe and effective first-line treatment option for elderly patients with metastatic colorectal cancer, potentially improving progression-free survival.
- What could go wrong
- This is an observational study, not a randomized trial, so results may be less definitive. The combination carries risks of chemotherapy side effects like nerve damage, fatigue, and gastrointestinal issues.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Istituto Oncologico Veneto IRCCS
Padua, 35128, Italy
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