New hope for duchenne kids: testing next treatment after gene therapy

NCT ID NCT06100887

Summary

This study is testing whether a daily oral medication called EDG-5506 is safe and can help control muscle damage in children and teenagers with Duchenne muscular dystrophy who have already received gene therapy. About 43 participants aged 6-17 will take either the medication or a placebo for 12 weeks, then all can continue taking the medication for up to 3 years. The research aims to see if this treatment can provide additional benefit to those who have already undergone gene therapy.

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Contacts and locations

Locations

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • Rare Disease Research

    Hillsborough, North Carolina, 27278, United States

  • UC Davis Medical Center

    Sacramento, California, 95817, United States

  • UCLA Medical Center

    Los Angeles, California, 90095, United States

  • University of Florida

    Gainesville, Florida, 32610, United States

  • University of Massachusetts Memorial Medical Center

    Worcester, Massachusetts, 01605, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.