Could a simple tablet protect your brain after a stroke?
NCT ID NCT06315231
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether a sublingual tablet called edaravone dexborneol can help prevent or reduce thinking problems that often occur after a stroke. About 226 people who recently had a stroke and already show some cognitive issues will take the tablet or a placebo twice daily for 24 weeks. Researchers will measure side effects and changes in thinking skills to see if the drug is safe and effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- edaravone dexborneol sublingual tablet
- What this could lead to
- If it works, this could lead to a new treatment to reduce cognitive decline after a stroke, helping people think more clearly.
- What could go wrong
- This is an early Phase II trial with only 226 people, so results may not apply to everyone. The drug may not improve cognition more than placebo, and side effects are still being studied.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Affiliated Hospital of Jining Medical College
RECRUITINGJining, Shandong, China
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Dongyang People's Hospital
RECRUITINGDongyang, Zhejiang, China
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Hefei First People's Hospital
RECRUITINGHefei, Anhui, China
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Huangshan City People's Hospital
RECRUITINGHuangshan City, Anhui, China
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Liaocheng People's Hospital
RECRUITINGLiaocheng, Shandong, China
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Liaoning Health Industry Group Bensteel General Hospital
RECRUITINGBenxi, Liaoning, China
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Suining Central Hospital
RECRUITINGSuining, Sichuan, China
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Tai'an Central Hospital
RECRUITINGTaian, Shandong, China
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Taihe County People's Hospital
RECRUITINGFuyang, Anhui, China
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The First Affiliated Hospital of USTC Anhui Provincial Hospital
RECRUITINGHefei, Anhui, China
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The First Hospital of Dalian Medical University
RECRUITINGDalian, Liaoning, China
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The First Hospital of Jilin University
RECRUITINGChangchun, Jilin, China
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The First People's Hospital of Huzhou
RECRUITINGHuzhou, Zhejiang, China
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The First People's Hospital of Shenyang
RECRUITINGShenyang, Liaoning, China
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The Second Affiliated Hospital of Guangzhou Medical University
RECRUITINGGuangzhou, Guangdong, China
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The Second Affiliated Hospital of Nanchang University
RECRUITINGNanchang, Jiangxi, China
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The Second Hospital of Hebei Medical University
RECRUITINGShijiazhuang, Hebei, China
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The Second People's Hospital of Hefei
RECRUITINGHefei, Anhui, China
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Wuzhou Red Cross Hospital
RECRUITINGWuzhou, Guangxi, China
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Zhuji People's Hospital of Zhejiang Province
RECRUITINGZhuji, Zhejiang, China
-
Zhumadian Central Hospital
RECRUITINGZhumadian, Henan, China
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Other studies related to the condition(s) this trial covers.
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