Could a simple tablet protect your brain after a stroke?

NCT ID NCT06315231

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a sublingual tablet called edaravone dexborneol can help prevent or reduce thinking problems that often occur after a stroke. About 226 people who recently had a stroke and already show some cognitive issues will take the tablet or a placebo twice daily for 24 weeks. Researchers will measure side effects and changes in thinking skills to see if the drug is safe and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

edaravone dexborneol sublingual tablet

What this could lead to

If it works, this could lead to a new treatment to reduce cognitive decline after a stroke, helping people think more clearly.

What could go wrong

This is an early Phase II trial with only 226 people, so results may not apply to everyone. The drug may not improve cognition more than placebo, and side effects are still being studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Hospital of Jining Medical College

    RECRUITING

    Jining, Shandong, China

    Contact Email: •••••@•••••

  • Dongyang People's Hospital

    RECRUITING

    Dongyang, Zhejiang, China

    Contact Email: •••••@•••••

  • Hefei First People's Hospital

    RECRUITING

    Hefei, Anhui, China

    Contact Email: •••••@•••••

  • Huangshan City People's Hospital

    RECRUITING

    Huangshan City, Anhui, China

    Contact Email: •••••@•••••

  • Liaocheng People's Hospital

    RECRUITING

    Liaocheng, Shandong, China

    Contact Email: •••••@•••••

  • Liaoning Health Industry Group Bensteel General Hospital

    RECRUITING

    Benxi, Liaoning, China

    Contact Email: •••••@•••••

  • Suining Central Hospital

    RECRUITING

    Suining, Sichuan, China

    Contact Email: •••••@•••••

  • Tai'an Central Hospital

    RECRUITING

    Taian, Shandong, China

    Contact Email: •••••@•••••

  • Taihe County People's Hospital

    RECRUITING

    Fuyang, Anhui, China

    Contact Email: •••••@•••••

  • The First Affiliated Hospital of USTC Anhui Provincial Hospital

    RECRUITING

    Hefei, Anhui, China

    Contact Email: •••••@•••••

  • The First Hospital of Dalian Medical University

    RECRUITING

    Dalian, Liaoning, China

    Contact Email: •••••@•••••

  • The First Hospital of Jilin University

    RECRUITING

    Changchun, Jilin, China

    Contact Email: •••••@•••••

  • The First People's Hospital of Huzhou

    RECRUITING

    Huzhou, Zhejiang, China

    Contact Email: •••••@•••••

  • The First People's Hospital of Shenyang

    RECRUITING

    Shenyang, Liaoning, China

    Contact Email: •••••@•••••

  • The Second Affiliated Hospital of Guangzhou Medical University

    RECRUITING

    Guangzhou, Guangdong, China

    Contact Email: •••••@•••••

  • The Second Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, Jiangxi, China

    Contact Email: •••••@•••••

  • The Second Hospital of Hebei Medical University

    RECRUITING

    Shijiazhuang, Hebei, China

    Contact Email: •••••@•••••

  • The Second People's Hospital of Hefei

    RECRUITING

    Hefei, Anhui, China

    Contact Email: •••••@•••••

  • Wuzhou Red Cross Hospital

    RECRUITING

    Wuzhou, Guangxi, China

    Contact Email: •••••@•••••

  • Zhuji People's Hospital of Zhejiang Province

    RECRUITING

    Zhuji, Zhejiang, China

    Contact Email: •••••@•••••

  • Zhumadian Central Hospital

    RECRUITING

    Zhumadian, Henan, China

    Contact Email: •••••@•••••