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Could a single drug halt devastating nerve attacks in NMOSD patients?

NCT ID NCT07184840

Recruiting now Disease control Sponsor: Tianjin Medical University General Hospital Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 27 times

Summary

This study tests whether eculizumab can quickly reduce disability during an acute attack of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune disease that damages the optic nerve and spinal cord. About 110 adults who test positive for a specific antibody (AQP4-IgG) and are having an attack will receive the drug. The main goal is to see if their disability score improves by at least 2 points within 28 days.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tianjin Medical University General Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, 300052, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

NEUROMYELITIS OPTICA SPECTRUM DISORDER ATTACK