New hope for Guillain-Barré? drug trial targets severe cases

NCT ID NCT04752566

First seen Nov 01, 2025 · Last updated May 06, 2026 · Updated 20 times

Summary

This study tested whether eculizumab can help people with severe Guillain-Barré syndrome (GBS), a rare nerve disorder that can cause paralysis. The trial included 57 adults in Japan who had severe symptoms and were already receiving standard treatment. The main goal was to see if eculizumab helped them recover mobility faster than a placebo.

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Contacts and locations

Locations

  • Research Site

    Bunkyō City, 113-8519, Japan

  • Research Site

    Chiba, 260-0877, Japan

  • Research Site

    Fukuoka, 814-0180, Japan

  • Research Site

    Hiroshima, 730-8518, Japan

  • Research Site

    Kagoshima, 890-8520, Japan

  • Research Site

    Kawagoe-shi, 350-8550, Japan

  • Research Site

    Kawasaki-shi, 216-8511, Japan

  • Research Site

    Kitakyushu-shi, 807-8555, Japan

  • Research Site

    Kobe, 650-0047, Japan

  • Research Site

    Kumamoto, 860-8556, Japan

  • Research Site

    Kurashiki-shi, 710-8602, Japan

  • Research Site

    Matsumoto-shi, 390-8621, Japan

  • Research Site

    Mitaka-shi, 181-8611, Japan

  • Research Site

    Nagoya, 466-8560, Japan

  • Research Site

    Niigata, 951-8520, Japan

  • Research Site

    Nishinomiya-shi, 663-8501, Japan

  • Research Site

    Sapporo, 060-8648, Japan

  • Research Site

    Sayama, 589-8511, Japan

  • Research Site

    Sendai, 983-8520, Japan

  • Research Site

    Shimotsuga-gun, 321-0293, Japan

  • Research Site

    Ube-shi, 755-8505, Japan

  • Research Site

    Yokohama, 236-0004, Japan

Conditions

Explore the condition pages connected to this study.